Biography
Bonnie Thiel is a biostatistician working in the Tuberculosis Research group at Case Western Reserve University. Starting as a bench scientist working on protein purification and characterization and later in a genetics lab, she continued her education and transitioned into statistics and data science.
Her main interest is in the application of statistics and bioinformatics tools to analyze experimental and population data. In her current position as a data analyst in the Tuberculosis Research Unit, she is working on the discovery of host biomarkers related to Mycobacterium tuberculosis (Mtb) infection and TB disease. From the pathogen side, she is doing comparative genomics of Mtb isolates to identify mutations that may lead to the discovery of new antibiotic candidates.
Download my resumé.
- bioinformatics tools and methods
- biostatistical applications
- systems immunology
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PhD in Systems Biology and Bioinformatics, 2021
Case Western Reserve University
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MS in Genetic Epidemiology, 1998
Case Western Reserve University
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BSc in Molecular Biology and Biochemistry, 1988
University of Colorado
Experience
Since 2002 I have been a data analyst in the Tuberculosis Research Unit at CWRU.
My responsibilities include:
- statistical support for lab experiments, observational studies and clinical trials.
- project and data management: overseeing the collection, storage and analysis of study data.
- Programming in R and SAS
- Analysis of large -omics experiments utilizing the Linux computing cluster at CWRU
- Design and maintenance of REDCap databases
From 1994 to 2002 I worked as a statistical geneticist in the department of Population and Quantitative Health Sciences at CWRU where I performed:
- genetic analysis of familial and population-based traits including bipolar disorder, prostate cancer, and hypertension
- candidate gene and genome-wide SNP, linkage and haplotype analysis
